Defective DePuy Metal-On-Metal Hip Implants May Result to Heavy Metal Poisoning

August 26, 2012

Metals Resources

Defective DePuy Metal-On-Metal Hip Implants May End result to Hefty Metal Poisoning


The hip implant metallosis is 1 of the several problems that came up right after DePuy Orthopaedics Inc.’s recall of its Articular Surface Replacement (ASR) hip techniques. Metallosis has also been between the allegations contained in the numerous lawsuits that have been filed against Johnson &amp Johnson, DePuy’s mother firm. Several of these lawsuits have been consolidated into a multidistrict litigation beneath Judge David A. Katz of the U.S. District Court for the Northern District of Ohio who named for a status conference ofthe DePuy hip substitute lawsuit this month.


The hip implant metallosis is the metal poisoning of cobalt and chromium in the soft tissue which could lead a patient to suffer pain and potentially dangerous side results.

Allegedly, the hefty metal construct-up, particularly of chromium and cobalt, in the tissue is caused by the defective design and style of the metal-on-metal (MoM) ASR hip implants. A report in the New York Instances stated that orthopedic experts said that they believed that the design and style of the ASR cup, which is shallower than some equivalent gadgets, was at the heart of the implant’s problems.


DePuy’s style of a shallower cup and removal of the plastic liner from the within of the implant was meant for sufferers to have a wider variety of motion. Even so, the friction of the ball portion of the hip implant against the socket wears away cobalt and chromium particles from the device and into the soft tissue around the region primary to metallosis.


The DePuy ASR hip implants use heavy metals cobalt and chromium since of their strength and anti-corrosion properties.

The presence of these heavy metals at a reduced degree in the body is considered protected, nonetheless, elevated ranges could be toxic for individuals as it could lead to the two cobalt and chromium poisoning. In cobalt poisoning, specialists think about any blood serum concentration at or over seven micrograms per millilitre to be unsafe.


Signs and symptoms of cobalt poisoning are:


•  Cardiomyopathy

•  Neuropathy

•  Kidney failure

•  Thyroid issues

•  Gastrointestinal difficulties

•  Haemorrhages

•  Optic nerve / vision issues

•  Deafness


Experts at the Mayo Clinic Health care Laboratories feel that even reduced ranges are concerning even if no particular concentrations have been established to be regarded as as harmful ranges for chromium poisoning, “blood serum concentrations increased than 1ng/ML in a affected person with Cr-primarily based implant propose substantial prosthesis put on.”


Chromium poisoning signs and symptoms may include:


•  Increased threat of cancers

•  Impaired liver perform

•  GI haemorrhage

•  Acute renal failure


A normal blood check could diagnose the two issues. A revision surgery would be essential to get rid of the defective hip implant that is leading to the poisoning on affected patients. In the encounter of the grave danger that the defective implants pose to a patients’ overall health, the ASR hip replacement recall appeared inadequate.


Uncover Far more Metal Content articles

, , , , , , ,

No comments yet.

Leave a Reply